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Jakarta, Sinar Harapan
Adams is now can stand them self if in future prostate cancer attack him. A study to find the genes found the reason what become nightmare for man.

For the Eve, the cancer can be a bad dream only breast cancer or womb neck cancer. For those of Adam, that nightmare is prostate cancer. In few last time, the disease what caused by the violence prostate gland cells at go more. Even though in Asia is still quite a bit of patients, 13 data from the Medical Faculty of the country in Indonesia shows cancer prostate including disease in top ten vicious disease for men. In Urology, surgery, the Faculty of Medicine, University of Indonesia (FKUI), during the period 1995-1998 found an average 17 cases per year and was ranked second after cancer in bladder. This number can not be ignored because the disease is killing about 10,000 men each case.

Gen E2F3
Now, thanks to results of studies conducted by scientists from the Institute of Cancer Research Everyman Center, the men can breathe a little relieved. They have to find the genes called E2F3, which is considered a triggered prostate cancer. E2F3 genes previously also detected as causes of bladder cancer. Indeed, these genes have an important role as a checker cell division in the body organism.
In the case of prostate cancer cells, E2F3 genes overactive this effect, which is producing too much protein. As a result there make excessive cell growth. Team of scientists have been measuring the womb E2F3 protein in the prostate 147 men and see how many E2F3 level in each cell. Found no one who prostate healthy cells. E2F3 genes thus are present as much as 67 percent of prostate cancer cells. The higher amount of protein, the more aggressive the cancer suffered.
"Significantly, this is quite brisk, as it is known. From here it can be a bookmarks in prostate cancer diagnosis, "said Professor Colin Cooper, head of study to BBC News Online. "The test to distinguish which aggressive tumor, the cause, which the tumor and light are important in prostat cancer research."
Often a patient going through the treatment procedure is indeed not necessary. However, because the diagnosis of cancer prostate not accurate then every such patient would not to do. Now that the genes already known E2F3 play an active role in prostat cancer as a key indication of how aggressive cancer developing.
PSA test
Until now, the majority of medical experts around the world use the tests Prostate Specific antigen (PSA) to know of the existence of prostate cancer. Less accurate the test is going to take serious action for the cancer that light. This test also can not afford to find out whether the cancer to grow quickly or slowly.
PSA is a single chain glycoprotein consisting of 237 amino acids and four carbohydrate side chains. PSA is located on the cells sekretik from asinine prostate so that PSA is a substance of a specific organ prostate, so can be found in the normal prostate, hyperplasia and prostate cancer prostate. PSA level in serum depends on the size of the prostate. Bigger on benign prostate, derived from the PSA transitional zone, but the cancer prostate be much higher.
Usually PSA level in serum measured by Radio Immune Assay (Ria). PSA in serum can also boast on conditions such as inflammation (prostatitis), the action Katter, rectal examination or sistoskopi and TURP (Trans Urethra Resection of the Prostate). While in the network prostate, PSA can be identified with the coloring Immune peroxides in pathology. PSA level is useful to follow the journey of prostate cancer response to treatment or surgery that was done.
In addition to being identified as a trigger prostate cancer, genes E2F3 is also considered as a cause of bladder cancer. Cancer is no less violent than prostate cancer. In Indonesia, based on results of examination of the data collection network that carried out during 1988-1990, it is known that bladder cancer ranks tenth of the primary malignant tumor in men. Actually this disease is not a disease of Adam only, but also the Eve. But the note indicates the man three times more risk of bladder cancer is exposed.
Cooper and the team find there is a huge amount of multiple genes of E2F3 in bladder cancer patients. From the analysis also demonstrated the direct relationship between the amount of E2F3 and stage of cancer. This invention can be expected soon to become a reference in bladder cancer treatment in the future. In addition to the genes of patients, also expected soon created boutique style treatment where treatment procedures are performed on each patient is different each other, determined by the level of gen assets.
"Medicine is much more effective because each patient can be know the genetic condition of them, whether it is classified as a potentially large contract cancer or not," said Cooper. This invention greeted both by cancer experts in the entire world. Professor Peter Rigby, the head of the Institute Cancer Research commented, "We await the findings of this study and can anticipate the development of cancer and bladder prostate earlier."
Prostate cancer is a malignant cancer that attacks the men are over 50 years. Usually if there are family members who prostate cancer carry the risk of other family members is also have high risk. Strangely this disease rarely what attack enough people in Asia. (SH / merry Magdalena)